The signal transducer and activator of transcription 5 (STAT5) regulates differentiation ... Wt Ba/F3 cells only survive and proliferate in presence of IL-3. In contrast, Ba/F3 cells transfected ...

2, and STAT5A and -5B are activated by binding to phosphorylated tyrosine residues on the receptors. A STAT5 dimer translocates to the nucleus and changes rates of transcription. STAT5 signaling ...