The invading T cells secrete interferon-γ, compromising neurogenesis and memory. This response was strongest in the hippocampus, where immune infiltrators kicked astrocytes and microglia into reactive ...

Methods. Cultured microglia, both N9 and primary derived lines, were treated with flavonoids in the presence of IFN-γ and/or CD40 ligation to assess any anti-inflammatory effects and/or mechanisms.