来自暨南大学生命科学与技术学院生命与健康工程研究所肿瘤分子生物学教育部重点实验室等多个单位的研究人员，在《Cell Death and Disease》期刊上发表了题为 “FAM210B activates STAT1/IRF9/IFIT3 axis by upregulating IFN-α/β expression to impede the progression of lung ...

In PD-1/PD-L1 immune checkpoint inhibitor cancer treatment, IFN-γ is a prognostic marker. The production of IFN-γ is associated with an improved response to immune checkpoint blockade (ICB ...

Ribavirin is a weak inhibitor, but is very synergistic when combined with interferon. The problem of ribavirin-induced anaemia led to the development of a prodrug (Viramidine; Valeant) that seeks ...

PEG-IFN (4 weeks) 3: Sofosbuvir + RBV (12 weeks) + PEG-IFN (8 weeks) 4: Sofosbuvir + RBV + PEG-IFN (12 weeks) Arm 3: treatment-experienced (17) Arm 1: ABT-450/r (250/100 mg) + ABT-333 + RBV × 12 ...

Recent advances using transgenic animals or exogenous complement inhibitors have demonstrated ... C57BL/6 mice deficient in interleukin12 or gamma interferon showed faster acute vascular rejection ...

Panelists discuss how the introduction of Janus kinase (JAK) inhibitor therapies will likely change treatment algorithms for alopecia areata (AA), with insights on how payers should plan for coverage ...

Groups 1–3 received PEG-IFN for 4, 8, and 12 weeks ... using mericitabine (nucleoside polymerase inhibitor) and ritonavir boosted danoprevir in G1 HCV have proved disappointing.

Panelists discuss how the Bayesian network meta-analysis showed which Janus kinase (JAK) inhibitors were most effective in ...

Interferon-gamma (IFN-γ/IFNG) is a dimerized soluble cytokine and the sole member of the type II interferon class. Originally referred to as macrophage-activating factor, IFN-γ is now recognized ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...