Millions of individuals rely on effective medications to manage diseases like cancer and diabetes. For those with chronic myeloid leukemia (CML), advancements in treatment selection could ...

Recent research has focused on synthesizing new compounds that can effectively inhibit this enzyme ... inhibition of α-glucosidase, with the most potent compound showing an IC50 value much ...

Sortase A (SrtA) is a critical enzyme found in Gram-positive ... with one compound achieving an IC50 of 18.9 µM[4]. Furthermore, a new class of inhibitors, 2-sulfonylpyrimidines, was identified ...