The replication of chromosomes in S phase and their segregation at mitosis ... of the disease and is dependent on the proper action of cell-cycle checkpoint controls. Where is cell-cycle research ...

Background: The Multicenter Study of Hydroxyurea (HU) in Sickle Cell Anemia (MSH ... double-blind, treatment phase. The effects of factors including randomized treatment, age, gender, pre ...

a milder form of sickle cell disease (SCD), a Ghanaian randomized phase II trial showed. Hematologic DLTs -- mostly mild and transient -- occurred in 33% of patients taking hydroxyurea compared ...