De Duve named these new organelles "lysosomes" to reflect their lytic nature. That same year, Alex Novikoff from the University of Vermont visited de Duve´s laboratory. An experienced ...

To pinpoint the individual components of the missing pathway, Tan used a lentivirus to express an enzyme called Turbo-ID in human cells, which sticks a biotin tag onto any protein within a ...

Each lysosome, about 0.1 to 1.2 micrometers in size ... say that it's a process of self-cleaning that happens within the ...

They found that a specific protein, ABCA1, which helps brain cells stay healthy, does not work properly in people at risk for ...

This bubble then merges with the lysosome, where the contents are broken ... leading to the buildup of waste inside cells and human diseases. "We're excited about the potential of this research ...

Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have made a breakthrough in ...