为探究胎儿基因 Pontin 在成年心脏中的作用,英国曼彻斯特大学的研究人员开展相关研究。结果发现 Pontin 可调节心肌细胞功能,或通过 Hippo 通路保护心脏。这一成果为防治心脏疾病提供新方向,极具科研价值,推荐大家阅读。
The lab reported in the journal Science that a gene pathway called Hippo inhibits cardiac muscle regeneration during development. View the Science Journal article. Our lab is currently working to ...
LATS1/2-inactivation and consequent nuclear YAP/TAZ hyperactivation in the mammary epithelium drives the development of a pro ...
Among these signals, the TGF-β and HIPPO pathways are critical, functioning as tumor suppressors and regulating liver development and regeneration. The review focuses on these pathways' interplay ...