The majority of diseases that lead to cirrhosis primarily affect the hepatocytes (hepatocellular diseases ... chronic viral hepatitis B, C, or D. Liver injury leading to cirrhosis also may ...

Hepatocellular necrosis, hepatitis, and cholestasis ... a few drugs shown to cause liver damage in patients using a particular metabolic pathway, idiosyncratic drug injury is unpredictable in ...

To investigate how the liver adapts to chronic obstructive cholestasis, liver samples from ... accumulating bile acid and metabolites injury at different stages of the disease.