The Hedgehog (Hh) pathway plays central roles in animal development and stem-cell function. Defects in Hh signalling lead to birth defects and cancer in humans. The first and often genetically ...

This new review article highlights the crucial role of GATA6, a transcription factor, in pancreatic ductal adenocarcinoma ...

Those cells travel to the cancer through what’s called the hedgehog pathway. The hedgehog pathway got its name because in early genetic studies, fruit flies with a certain genetic mutation had ...

The aPKCi inhibitor platform targets a group of cancers linked to the hedgehog signaling pathway, including basal cell carcinoma, medulloblastoma, small cell lung cancer, rhabdomyosarcoma ...

This new review article highlights the crucial role of GATA6, a transcription factor, in pancreatic ductal adenocarcinoma (PDA). The article explores ...