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HOXB4/METTL7B 级联通过 TKT m6A 修饰调控肝癌恶性表型,有望成为肝癌 ...
为探究 HOXB4 对肝癌的影响,研究人员发现 HOXB4/METTL7B/TKT 轴调控肝癌恶性表型和免疫逃逸,为治疗提供新靶点。 肝癌(Hepatocellular carcinoma,HCC)是全球范围内导致癌症相关死亡的主要原因之一,尽管在诊断、手术、靶向治疗和免疫治疗等方面取得了进展 ...
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