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HK2 介导的肝脏巨噬细胞代谢应激与炎症:MASLD 治疗新靶点的探索
为探究代谢功能障碍相关脂肪性肝病(MASLD)的发病机制,南京师范大学等机构的研究人员开展了关于肝脏巨噬细胞中 HK2 相关反馈环的研究,发现 HK2/glycolysis/H3K18la 正反馈环加剧 MASLD 病情,阻断该环可缓解疾病,为 MASLD 治疗提供新策略。 代谢功能障碍相关脂肪 ...
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