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腾讯网
23 小时
攻克HER2阳性乳腺癌:探索HER2双靶向治疗的潜力
*仅供医学专业人士阅读参考一文解读抗HER2双靶向抑制的协同作用、患者筛选和耐药机制。HER2阳性乳腺癌是一种由HER2基因驱动的癌症,抗HER2靶向治疗通过阻断HER2下游的致癌酪氨酸激酶信号传导路径的激活和诱导免疫介导的细胞死亡来发挥作用。双重H ...
腾讯网
8 天
荟萃分析验证ADC相比其他抗HER2疗法能为HER2阳性晚期乳腺癌带来显著 ...
ADC高效低毒,成为HER2阳性晚期乳腺癌患者的优选方案。人表皮生长因子受体2(HER2)在大约20-25%的乳腺癌中扩增或过表达,与乳腺癌细胞的增殖和侵袭能力密切相关[1]。其生物学行为表现为高复发、转移、耐药和预后不良[2]。常规治疗包括大分子单 ...
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