Schematic representation depicts the mechanism by which the ENO2-derived oncometabolite PEP directly binds to HDAC1 and thereby promotes H3K18la, which promotes macrophage polarization and leads ...

A new study published in Engineering has identified enolase 2 (ENO2) as a key factor in the lymphatic metastasis of head and ...

为探究胆红素脑病（BE）中星形胶质细胞焦亡的调控机制，研究发现 H3K18 乳酸化（H3K18la）/NOD2 轴参与其中，或为治疗提供新策略。 在新生儿的世界里，有一种常见现象 —— 新生儿高胆红素血症，它就像潜伏在宝宝健康路上的 “小怪兽”。大约 60% 的足月儿和 80 ...

A recent study published in Engineering has shed new light on the mechanisms underlying the metastasis of head and neck squamous cell carcinoma (HNSCC). The research identified enolase 2 (ENO2), a ...