for 8 h at 37 °C. At the 4-hour time point, monensin (Sigma) was added, at a final concentration of 1 μm. At the 8-hour time point, cells were washed twice and stained for CD3 surface antigen ...

The immune response depends upon coordinated recognition both of intact and fragmented forms of protein antigens. T lymphocytes use T cell antigen receptors (TCRs) to recognize peptides associated ...

Recipient T cells recognize donor antigens via two distinct pathways: the direct pathway (intact donor MHC molecules displayed on donor antigen-presenting ... T-cell recognition of donor MHCs ...

In a recent study published in Nature Biotechnology, researchers describe the molecular structure of targeted recognition of antigen-MHC complex ... In diseased cells, multiple aberrant proteins ...