Allopurinol and its principal metabolic product, oxipurinol (alloxanthine, oxoallopurinol), inhibit the enzyme, xanthine oxidase, that normally converts hypoxanthine to xanthine, and xanthine to ...

With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans. Now, researchers at Harvard University have designed a new class ...

In addition to the five nitrogenous bases—adenine, guanine, cytosine, thymine and uracil—required for building DNA and RNA, the researchers also found xanthine, hypoxanthine, and nicotinic ...