在肝缺血再灌注损伤中，铁死亡为细胞主要死亡形式。DNA甲基化和GPX4启动子高甲基化参与HIRI诱导铁死亡的发生。本研究结果 ...

通过 MTT 检测和 EdU 检测来评估细胞增殖情况；采用流式细胞术分析细胞凋亡；利用 ELISA 试剂盒检测炎症因子浓度；使用相关商业试剂盒测定铁死亡相关标志物；运用 qRT-PCR 和蛋白质免疫印迹法（western blot）测量乳腺癌 1 号基因相关蛋白 1（BRCA1-associated protein 1 ...

One such protein, glutathione peroxidase 4 (GPX4), is vital in supporting cellular protection and cancer cell survival. "This protective property of GPX4 creates a significant challenge for ...

It's still an open question why non-hibernator cells are much more vulnerable to cold stress than hibernator cells even ...