One of the most important metabolic links between neurons and astrocytes, however, is the glutamate–glutamine shuttle. Astrocytes transport the vast majority of extracellular glutamate ...

We have investigated the role of mitochondrial calcium buffering in excitotoxic cell death. Glutamate acts at NMDA receptors in cultured rat forebrain neurons to increase the intracellular free ...

Astrocytes are the largest ... in male mice by increasing extracellular glutamate and synaptic transmission, highlighting a key role of astrocyte-neuron interactions in chronic pain.

In the brain, one way that neurons communicate with one another is through secretion of glutamate. Astrocytes, a type of glial cell, mop up extra glutamate, convert it to glutamine—the precursor for ...

We are broadly interested in the question of how interactions between cells within the brain (particularly between astrocytes and neurons) influence physiology and behavior ... The movie shows ...

This finding aligns with previous observations that neuronal excitation stimulates glioma growth and that neuron–glioma communication involves glutamate. Subsets of the far-reaching glioma ...

D.W. Choi, "Glutamate neurotoxicity and diseases of the nervous system," Neuron, 1, 623-34, October 1988. Dennis Choi (Stanford University, Calif.): "I think that citation of this review article ...