Hosted on MSN1mon
Molecular mechanism reveals how hairy mussels achieve reversible underwater adhesion
Their findings, published in Nature Communications, reveal an oxidation-independent adhesion process driven by interactions between EGF/EGF-like domains and GlcNAc-based biopolymers. Marine ...
Hosted on MSN2mon
Embryo development hinges on sugar-modified proteins, study demonstrates
More information: Sara Formichetti et al, Genetic gradual reduction of OGT activity unveils the essential role of O-GlcNAc in the mouse embryo, PLOS Genetics (2025). DOI: 10.1371/journal.pgen.1011507 ...
Nature3mon
A sugar-coated switch for cellular growth and arrest
The reversible attachment of an activated form of N-acetylglucosamine (UDP-GlcNAc) acts as a molecular switch between the growth and arrest of cells, establishing a new role for cell surface glycans.