Patients with generalized pustular psoriasis experienced flares despite the use of traditional off-label therapies and frequently changed treatment.

泛发性脓疱型银屑病（generalized pustular psoriasis，GPP）是一种罕见、可危及生命的、系统性中性粒细胞性皮肤病，发作时主要表现为全身红斑和脓疱并伴随全身系统性炎症症状，如发热、关节痛、肌痛、C 反应蛋白升高、白细胞增多等 ...

Boehringer Ingelheim announced new analyses to be presented at the American Academy of Dermatology (AAD) annual meeting in Orlando that explore the effect that SPEVIGO® (spesolimab-sbzo) may have on ...

Generalized pustular psoriasis (GPP) is a serious and rare form of psoriasis that can cause systemic symptoms. Because GPP can be life threatening, hospitalization may be necessary when a flare ...

GPP can be triggered by the initiation and withdrawal of various medications, in particular the withdrawal of corticosteroids, and by infections, stress, and other conditions. 1,5,6,10 Patients ...

GPP是一种罕见且可危及生命的皮肤病，若不及时控制可能会导致败血症和多系统器官衰竭，危及生命。因此，快速控制GPP的急性发作是治疗的关键。公告指出，HB0034作为国内首个自研创新抗IL-36R抗体，通过抑制IL-36通路发挥抗炎的生物学效应。临床试验结果显示，相比于安慰剂，HB0034单次静脉给药后的第1周，GPP发作患者的皮肤脓疱得到明显清除，达到方案预设的主要研究终点，且安全性方面表现良好， ...

Generalized pustular psoriasis (GPP) can range in severity and may be life threatening for some people. Treatment typically includes a variety of topical, oral, and injectable medications.

Generalized pustular psoriasis (GPP) is considered a rare and severe form of psoriasis that may be treated with a combination of oral medications, topical treatments, and more. Generalized ...

"Vanda and AnaptysBio link for generalised pustular psoriasis therapy" was originally created and published by Pharmaceutical Technology, a GlobalData owned brand. The information on this site has ...

Suggested remit: To appraise the clinical and cost effectiveness of spesolimab within its marketing authorisation for treating generalised pustular psoriasis flares in adults.