In this type of diabetes, the immune system specifically destroys insulin-secreting beta cells in the pancreatic islets — the body's own immune system attacks its own cells (a form of autoimmune ...

Increased levels of glucose in the circulation lead to increased glucose uptake into pancreatic beta cells through GLUT2, a glucose transporter. Increased intracellular glucose then leads to ...

With non-existent to mild symptoms, hyperglycemia is often revealed in routine screening. Glucokinase (GCK) is the enzyme which sensors glucose level in pancreatic beta cells. If glucose reaches the ...

This balance is disturbed in diabetes, leading to serious health issues. Beta cells in the pancreas manage this balance by releasing insulin when blood sugar levels rise. Understanding how beta ...