Adenoviral vectors will transduce a wide range of target cells resulting in high-level gene expression. They are non-integrating vectors so expression in dividing cells is progressively lost. First ...
Ad5 vectors are the most commonly used adenovirus vector. Ad5 vectors transduce a wide range of cell types. They utilize the Coxsackie-Adenovirus Receptor (CAR) to enter cells. Transduction efficiency ...