GPCRs are the targets for around one third of all approved drugs 1. Yet such medicines act on only a handful of the 800+ known GPCRs. A wave of biomedical progress in the early 21 st century ...

The GAIN domain plays a central role in the activation of adhesion GPCRs. Until now, research has been limited by the low similarity of the amino acid sequences of different GAIN domains, which has ...

The GAIN domain plays a central role in the activation of adhesion GPCRs. Until now, research has been limited by the low similarity of the amino acid sequences of different GAIN domains ...

The GAIN domain plays a central role in the activation of adhesion GPCRs. Until now, research has been limited by the low similarity of the amino acid sequences of different GAIN domains ...

The GAIN domain plays a central role in the activation of adhesion GPCRs. Until now, research has been limited by the low similarity of the amino acid sequences of different GAIN domains ...

The diversity and near universal expression of G protein-coupled receptors (GPCR) reflects their involvement in most physiological processes. The GPCR superfamily is the largest in the human ...