But how does this happen? "It is as if G-protein signaling causes the channel to need more 'persuasion'—in terms of stronger electrical signals—to open. In our study, we describe at the ...

Other signaling molecules must move much farther ... Membrane receptors fall into three major classes: G-protein-coupled receptors, ion channel receptors, and enzyme-linked receptors.

However, the mechanism by which heterotrimeric G proteins are activated by their ... are sophisticated allosteric machines with multiple signaling outputs. You have full access to this article ...

A basic function of cells is that they act in response to their environments. It makes sense, then, that a goal of scientists ...