Internal tandem duplication (ITD) mutation in Fms-like tyrosine kinase 3 gene (FLT3/ITD) represents an unfavorable genetic change in acute myeloid leukemia (AML) and is associated with poor prognosis.

FMS-like tyrosine kinase 3 ligand (FLT3LG), also known as FL, Flt3L, and FLT3LG, is an α-helical cytokine crucial for the differentiation of multiple hematopoietic cell lineages. It is expressed ...