FMR1 gene: A gene located on the X chromosome ... R-loop: A three-stranded nucleic acid structure formed during transcription when RNA hybridizes with the DNA template strand.

Select the journal/section where you want your idea to be submitted: Fragile X Syndrome (FXS), the most common form of inherited mental retardation, is caused by a trinucleotide repeat expansion (CGG) ...

Dr Dean, Department of Medical Genetics, Medical School, Foresterhill, Aberdeen AB25 2ZD, UK. We report a 13 year old boy with fragile X syndrome resulting from a de novo deletion of the FMR1 and FMR2 ...

Sacramento, CA 95817, USA; ftassone{at}ucdavis.edu Background Greater than 200 CGG repeats in the 5′UTR of the FMR1 gene lead to epigenetic silencing and lack of the FMR1 protein, causing fragile X ...