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敲开脆性 X 综合征的新 “视窗”:小胶质细胞中 Fmr1下调对小鼠行为 ...
为探究小胶质细胞中 Fmr 1 表达降低是否导致分子和行为表型,研究人员下调其表达,发现会引起雌性小鼠行为改变,意义重大。 在神经发育的奇妙 “舞台” 上,脆性 X 综合征(Fragile X syndrome,FXS)作为一种常见的遗传性神经发育障碍,一直是科学家们重点关注 ...
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