The key cellular constituents of these new capillaries are endothelial cells: their interactions with soluble biochemical and insoluble extracellular matrix (ECM) proteins have been well documented ..

Consideration of how the extracellular matrix directs cell behavior will be ... in which to consider dynamic reciprocity. In the model of dynamic reciprocity cells communicate with their ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including milk thistle, turmeric, and green tea, that target the tumor ...

Researchers develop 3D blood-brain barrier model to study Alzheimers and neuroinflammation New platform created to improve ...

The Under-oil Open Microfluidic System enhances tumor cell-ECM interaction studies, improving anti-metastatic drug testing ...

The extracellular matrix (ECM) is a complex cell-secreted network composed of a diverse array of ... who are already familiar with their journal's scope, ethos, and publishing model. All other topics ...

All of these cell properties are closely controlled by cell–cell and cell–matrix interactions and as such the physical geometry of the whole tumour will be dependent on these individual cell ...

Aberrant expressions of matrix proteins by cancer-associated fibroblasts (CAFs) alter the mechanical properties of the tumor extracellular matrix (ECM ... In an orthotopic xenograft model of human ...

Osteoarthritis (OA) is a condition that disproportionally affects postmenopausal women, and the millions affected can attest ...

This study examines the role of an abundant extracellular matrix component, the megadalton glycosaminoglycan hyaluronan (HA), as a novel therapeutic target in PDA. Methods Using a genetically ...