Background: Infections caused by extended-spectrum β-lactamase (ESBL)–producing gram-negative organisms are a growing concern in hospitalized patients. Traditionally, these infections can be ...

8). Figure 1: A sequence alignment of amino-acid residues near the H-9 (α9) and H-10 (α10) helix of class C β-lactamases with extended substrate spectrum.

and antimicrobial resistance to ciprofloxacin and extended-spectrum beta-lactamase [ESBL] production. We analyzed resistance rates (by patients-day) in the cohort, as well as in other patients ...

Antibiotic-resistant E. coli is increasingly common. Strains which have 'Extended Spectrum Beta-Lactamases (ESBLs) - enzymes that destroy penicillin and another antibiotic, cephalosporin - are ...