Most of these are ex vivo gene-therapy products in which a patient ... after which they are transduced with a retroviral or lentiviral vector carrying a therapeutic DNA insert, before being ...

Pfizer is pulling further away from the gene therapy field with its decision to discontinue hemophilia product Beqvez. | ...

Mustang’s lead gene therapy program is a lentiviral gene therapy for XSCID developed in collaboration with St. Jude. The therapy involves ex vivo lentiviral transduction of the patient’s own ...

Lentiviral vectors (LVVs ... number of commercial advanced therapy technologies, from chimeric antigen receptor (CAR) T-cell therapies to ex vivo gene therapies and, earlier last year, the ...

They can perform additional in vitro or ex vivo testing to help reduce the risks ... such as those offered by Charles River as a part of their gene therapy products and services portfolio. The company ...

The companies all use modified versions of the same lentiviral vectors used in ex vivo CAR-T therapy ... really of transforming in vivo gene therapy in general as we move forward and get ...

The investigators showed that lentiviral transduction was enhanced ... "This is an exciting advancement for both ex vivo gene therapy in general and for improving treatment for patients with ...

Viral gene delivery is a ubiquitous laboratory technique with a myraid of uses. Understanding the basics of gene delivery workflows, from vector selection and cloning ...

R esearch led by Christian Medical College in Vellore, India, has demonstrated the successful use of lentiviral vectors to deliver gene therapy for patients with severe hemophilia A. The study ...