Lissencephaly is a devastating genetic disease of children that affects the embryonic development of the brain. It is caused by haploinsufficiency of the Lis1 gene product, which seems to be ...

Over the course of 40 days, the cells within the organoid self-organized into structures that resembled the early stages of brain and spinal cord development in a human embryo. This included the ...

In humans, the marks—a unique type of methylation—were known only to exist in embryonic stem cells before the new survey of neurons ... t know there was a drastic change in these marks in neurons ...

Nebraska’s K-12 schools would be required to teach students from elementary to high schools about human development under a ...

Once dismissed as the 'dark side' of the genome, researchers have now revealed their crucial role in early embryo development. Over half of our genomes consists of thousands of remnants of ancient ...

In this study, we identified neuronal precursors that can disperse through adult mammalian brain tissue. Transplanted neuronal precursors from embryonic medial ganglionic eminence (MGE), but not ...

Protein modifications are key to cell survival because they ensure they do what they are supposed to do in a healthy system.

The development ... from embryonic stem cells," Prof Zernicka-Goetz told the Guardian newspaper. She has already developed synthetic mouse embryos with evidence of a developing brain and beating ...

The Deneen Lab seeks to unlock the enigmatic biology surrounding glial cell development and function in the brain. Beginning with developmental gliogenesis, we identified the key transcriptional ...