细胞周期调节因子的适当调控对于病毒复制和宿主植物适应性生长在病毒感染过程中至关重要。然而，宿主-病毒相互作用中重新编排视网膜母细胞瘤相关蛋白1（RBR1，E2F转录因子的抑制因子）及其下游基因的机制尚不清楚。 细胞分裂周期20（CDC20）通过E2F转录 ...

inhibiting the G1/S transition and causing G2/M arrest during cell cycle progression. The cycle progression is extensively controlled by the pRB/E2F signaling pathway. E2F is released from the pRB ...

One downstream consequence of RB activity is the inhibition of E2F activity, which is important for the transcription of several genes that are required for progression through the G1 and S phases ...