Science 234, 1582–1585 (1986). Contopoulou, C. R. et al. Analysis of DNA double strand breakage and repair using orthogonal field alternation gel electrophoresis. Yeast 3, 71–76 (1987).

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

The newly synthesized DNA (light blue) can then be joined with the 5' end of the resected strand, forming a double Holliday junction (double-strand break repair; DSBR), or can be displaced and ...

The DNA repair and replication pathways converge on a common final step in which the continuity of the repaired DNA strand is restored by DNA ligase, an enzyme that converts nicks into phosphodiester ...

RNA is one of the bodies most vital molecules, and it comes in a few forms. Many of them are crucial. | Cell And Molecular ...

The Arnoult lab focuses on genome stability, DNA repair and telomere biology. We study the different types of pathways that cells use to repair DNA double strand breaks, and how telomeres escape these ...

The requested information must be provided to the core and the core must approve the approach prior to proceeding to the next steps. For cytoplasmic injections the mix will contain the guide RNA(s), ...

A multi-institutional team of researchers, led by Georgia Tech's Francesca Storici, has discovered a previously unknown role ...

RNA’s Surprising Role in DNA Repair New insights could lead to improved treatments for cancer and other diseases. Francesca ...