This may hint at what lies ahead as we navigate the (mostly erroneous) tendency to identify every cell death process in drug hepatotoxicity and other liver diseases as ferroptosis. DILI is broadly ...

Two weeks to complete cell culture The DILI test can determine the toxicity of various entities (small molecules, proteins, ASOs, AAVs, etc.) in the presence or absence of liver disease.

Drug-induced liver injury (DILI ... Autoimmune Hepatitis (AIH): A chronic disease in which the immune system attacks liver cells, leading to inflammation and liver damage. Roussel Uclaf Causality ...

Drug-induced liver injury (DILI) is common because it can be caused by different pharmacological agents from nearly all classes of medications, including hepatotoxic drugs, anesthetics, anticancer ...

Derisking of drug-induced liver injury (DILI) continues to be a challenge for pharmaceutical scientists. Join Michael Hafey, Principal Scientist at Merck, as he discusses how to utilize a two-tiered ...

For drug-induced liver injury or alcohol-related liver diseases, cessation of taking causal agents, namely drugs for drug-induced liver injury or alcohol for alcohol-related liver diseases ...

USA: The American Glaucoma Society (AGS) and the American Academy of Ophthalmology (AAO) have issued a position statement emphasizing the need for caution in using nicotinamide, a derivative of ...

DILI is broadly categorized into intrinsic ... ferroptosis is increasingly implicated in various diseases, including liver injury. However, the liver's robust antioxidant defenses, including ...