PCR—the workhorse of modern molecular biology—is charging forward using both conventional and digital methods to explore single cells and even single molecules. Nathan Blow reports. In late ...

He needed a more sensitive detection method and turned to digital PCR (dPCR), discovering that it was able to detect viruses in samples that were negative with qPCR 2, 3. The principle behind dPCR ...

While real-time PCR is still the gold standard for quantifying therapeutic viral vectors like AAV used in cell and gene treatments, digital PCR (dPCR) offers considerable benefits for quantifying ...