To study the mechanisms by which transcriptional deregulation causes neoplasia, we are using a chromatin immunoprecipitation protocol to complement three different types of gene expression profiling.

These differences in chromatin conformation help determine which genes are expressed in different cell types, or at different times within a given cell. “Chromatin structures play a pivotal role ...

Zhang and his colleagues designed a generative AI model called ChromoGen to quickly ‘read’ DNA sequences and predict the ...