Chicken or egg In 2008, researchers found the first compelling evidence that extra centrosomes could drive tumor formation in flies. However, subsequent studies in mice failed to replicate the results ...

c-Jun is essential for liver carcinogenesis induced by DEN in the mouse model. [80] Sustained JNK activation via reactive oxygen species (ROS) in the setting of obesity and IR not only promotes ...

Figure 2: Targeted mutation of the Mgat5 locus in mice. Figure 4: PyMT-dependent tumor growth is suppresses ... the monomers incompetent for filament formation, was added to cells at a ...

but had profound effects on cholesterol metabolism in mice fed the HF/HC diet, including resistance to diet-induced hypercholesterolemia and cholesterol-gallstone formation. The underlying ...

Researchers have developed a new method to grow T cells that have greater longevity and can more efficiently destroy cancer cells in mouse models ... conditioned cells induced robust immunologic ...