Darier disease (DD), also known as keratosis follicularis, is a rare genetic skin disorder caused by mutations in the ATP2A2 gene. This condition is characterized by the presence of warty lesions ...

as well as Darier disease, a rare condition that causes scaly skin papules. TMB-001 is an ointment formulation of the well-established dermatology therapy isotretinoin, which LEO picked up for a ...

which occurs primarily in individuals with atopic dermatitis and skin diseases, such as pemphigus, Darier disease or traumatic burns. Defective cytokine secretion and decreased cell-mediated ...