Science 234, 1582–1585 (1986). Contopoulou, C. R. et al. Analysis of DNA double strand breakage and repair using orthogonal field alternation gel electrophoresis. Yeast 3, 71–76 (1987).

Destruction of islet cells with streptozotocin in mice induced hyperglycemia, intravascular oxidant production, DNA strand breakage, PARP activation and a selective loss of endothelium-dependent ...

Single-strand breaks generated during DNA repair ... "The paper is a nice study of the steady-state level of DNA breakage in brain and supports the long-held view that oxidative stress is a ...

In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks (DSBs) formation. Meiosis, a specialized form of cell division in most ...

The two strands of the DNA helix are unzipped by breaking of the weak Hydrogen bonds ... RNA polymerase moves along the DNA strand. Free RNA nucleotides form hydrogen bonds with the exposed ...

resulting in DNA damage in the form of loss of helical structure, impaired template function, and strand breakage, which eventually leads to cell death. Tinidazole was approved by the FDA in May ...