Guarding genes against damage is a crucial and complex job, so it’s to be expected that cells have several mechanisms to repair ... of DNA-interacting proteins, rather than their static ...

However, deletion of the LIG4 gene elicits phenotypes indicating that ligase IV catalyzes the repair of double-strand breaks in the non-homologous ... OH side of the nick and 11 to 12 nucleotides on ...

We know that if a DNA repair gene is mutated, cells become more sensitive to DNA damaging agents. Researchers in the 1960s isolated the first radiation-sensitive mutants in yeast. By the 1970s ...

An updated inventory of about 150 human DNA repair genes was recently compiled by ... that results in major distortion of the DNA structure. The basic process involved in this pathway consists ...

After all, the cell must repeat its whole genetic material, including billions of genetic letters, before it can divide. Read ...

Characteristics are passed from parents to offspring. A gene is a small section of DNA that codes for a characteristic (e.g. eye colour). Alleles are different forms of the same gene, for example ...