A single DNA nucleotide, the base unit of the human genome, is a tiny, tiny thing. Each one is made up of only 30 atoms (plus or minus a few, depending on the base), making it much too small to be ...

DNA sequencing is a laboratory method used to ... which is required to form a link with the next nucleotide in the chain. Since the ddNTPs are randomly incorporated, synthesis terminates at ...

Base substitutions are the simplest type of gene-level mutation, and they involve the swapping of one nucleotide for another during DNA replication. For example, during replication, a thymine ...