Northwestern Medicine investigators have discovered new mechanisms underlying cellular adhesion and repair, findings that ...

These MO-treated embryos showed cytokinesis failure that could be rescued by injecting wild-type MgcRacGAP mRNA lacking the 5′-UTR, but not by injecting two mutated mRNAs: one containing a ...

Thus, true failure of cytokinesis could be more extensive than the data would indicate. The lack of centrioles could therefore prevent cytokinesis in all acentrosomal cell systems examined.