Our work showed that CDK5 is activated by cyclin B1 and is required for proper cell division in non-neuronal cells. Indeed, like CDK1, CDK5 is also a canonical cell-division-cycle CDK. We have ...
Cyclin-dependent kinases (CDKs) are protein kinases involved in critical cellular processes, such as cell cycle or transcription, whose activity requires association with specific cyclin subunits.