Task1 goal: According to Gardinaer-Garden and Frommer's paper, find the CpG islands in the first 1,000,000 base paris of human chromosome 20. Download the pG islands sequence from UCSC Genome Browser, ...

Methylation knocks out gene function; methyl groups placed on CpG islands (relatively rare clusters of cytosine and guanine bases connected by a phosphorylation site) effectively prevent gene ...

When methylation affects CpG islands, methyl-binding proteins trigger a silencing cascade (activity illustrated by green stars) whereby histone H3K9 is sequentially deaceylated and then methylated ...