Translation of that understanding into clinical reality has been and remains difficult and is the subject of this commentary. Experimental exploration of cancer immunity in mice led to the ...

In two new papers, researchers from The Jackson Laboratory (JAX) report the successful use of two approaches -- gene therapy ...

two key points when considering the potential clinical relevance are that these studies are done in animal models, and that they are of behaviour, not disorders or even symptoms. Churchland seemed to ...

In a study published yesterday (August 5) in Science, researchers identify human and mouse long noncoding RNAs, whose loss mimics the metabolic disorder phenylketonuria (PKU) in human cells and mice.

In two new papers, researchers from The Jackson Laboratory (JAX) report the successful use of two approaches—gene therapy and ...

A dysfunctional signaling pathway in the hippocampus has been linked to chronic pain-related memory impairment in mice.

Researchers at Cedars-Sinai developed PR-364, a drug that prevented heart failure in mice after heart attacks. The treatment ...

In laboratory tests, mice with Parkinson’s-like symptoms received a single injection ... stability of the nanoparticles suggest potential clinical viability. This system also represents a ...