primary cilia can simultaneously support major IFT functions of the cell (Figure 3). The primary cilium has gone from being an oddity, with no known function, to an organelle that is at the center ...

The Hedgehog (Hh) pathway plays central roles in animal development and stem-cell function. Defects in Hh ... trafficking events at the primary cilium promises to shed light on the biochemical ...

Many cells in our body have a single primary cilium, a micrometer-long ... leaving their organization and function unclear. In a new series of work, researchers at HHMI's Janelia Research Campus ...

Dysfunctions of the tiny cell processes (primary cilia) of the pancreatic beta cells could be a cause of type 2 diabetes.