However, the presence of nucleosomes and the folding of chromatin into 30-nanometer fibers pose barriers to the enzymes that unwind and copy DNA. It is therefore important for cells to have means ...

The five phases of mitosis and cell division tightly coordinate the movements ... During interphase, individual chromosomes are not visible, and the chromatin appears diffuse and unorganized.

Chromatin, the name for this packaging ... on these pathways and the ways that DNA packaging can regulate cell division. This knowledge could one day aid in the development of new treatments ...

In their paper in Science Advances “ChromoGen: Diffusion model predicts single-cell chromatin conformations,” senior author Zhang, together with co-first author MIT graduate students Greg ...

Igal Szleifer, Ph.D., professor of Medicine in the Division of Pulmonary ... form chromosomes within the nucleus of cells. The scientists observed that chromatin self-organizes into "packing ...

In  a  paper  published  on  aBIOTECH,  the  authors  revealed  the  joint  regulation  of  chromatin structure and gene expression by BMI1s, the core components of Arabidopsis PRC1, and the condensin ...

Researchers say if their results are confirmed through further study they are optimistic the approach could be used to treat chronic infections for the first time.