Chromatin immunoprecipitation (ChIP) is a technique for identifying and characterizing elements in protein-DNA interactions involved in gene regulation or chromatin organization. Microarray ...

To study the mechanisms by which transcriptional deregulation causes neoplasia, we are using a chromatin immunoprecipitation protocol to complement three different types of gene expression profiling.

To do so, they planned to stabilize proteins at their chromatin binding locations and use nucleic acid hybridization to ... problem presented itself at a seminar where he learned that researchers ...

But the technique, called chromatin immunoprecipitation (ChIP), wasn't working very well, Paro says. "After the crosslink and immunoprecipitation, we realized we would only have very little DNA ...

They also performed chromatin immunoprecipitation followed by sequencing to assess the distribution of CENH3 in the genome. A validated anti-CENH3 antibody was used to isolate centromeric chromatin.