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The compounds are oral small molecules based on three distinct mechanistic platforms: calcitonin gene-related peptide (CGRP) receptor antagonists, glutamate modulators, and myeloperoxidase inhibitors.

The compounds are oral small molecules based on two distinct mechanistic platforms: calcitonin gene-related peptide (CGRP)- receptor antagonists, and glutamate modulators. Both therapeutic ...

Both belong to a newer class of drugs known as calcitonin gene-related peptide (CGRP) receptor antagonists. Though they share similarities, Ubrelvy is designed specifically for acute treatment ...

Compared with placebo, zavegepant nasal spray yielded sustained relief of acute pain and function in migraine.

Learn how Aimovig for migraine works, how well it works, what to know before starting, and its possible side effects. Experts and community members also weigh in about their experiences with Aimovig.

Sometimes people with very mild migraine symptoms do not improve with OTC treatments and need to take triptans or CGRP antagonists for relief. Severe migraine episodes, characterized by intense ...

Artemin reverses pain and neurochemical changes after nerve injury in an animal model. The molecule could potentially treat neuropathic pain, in which even the slightest touch can hurt. To evoke ...