a cellular macromolecule or an assembly of macromolecules that is concerned directly and specifically with chemical signaling between and within cells. Heteromeric receptor: Dimeric or oligomeric ...

We use a combination of biochemistry, genetics, and live imaging, primarily in the fruit fly nervous system (but also in mammalian cultured cells) to unravel the molecular mechanisms by which the ...

The Glial cell line-Derived Neurotrophic Factor (GDNF ... When searching for new receptors for GFLs we identified Syndecan-3 [8] as the binding and signaling receptor, and SorlLA as a sorting receptor ...

now called SNIPRs (synthetic intramembrane proteolysis receptors), which can bind to soluble, or free-floating, molecules in ...

Bitter taste receptor has hidden intracellular pocket that enables activation via simultaneous extracellular/intracellular ...

Weill Cornell Medicine researchers have determined the full-length structure of a blood pressure-regulating hormone receptor ...

Campus Chemical Instrument Center, Mass Spectrometry & Proteomics Facility, The Ohio State University, Columbus, USA ...

A review discussing the therapeutic potentials of NK cell biology has been published in the journal Frontiers of Medicine.

Immune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, ...

Natural killer (NK) cells play an important role in the innate immune response to cancer and viral infections, and their ...

Researchers developed SNIPRs, innovative receptors that sense soluble ligands, enabling precise therapeutic control in CAR ...