The first part of this special issue consists of 7 review articles covering diverse areas of research on cell signaling and disease. MAPK signaling is the prototype cellular signaling cascade.

Receptors are generally transmembrane proteins, which bind to signaling molecules outside the cell and subsequently transmit the signal through a sequence of molecular switches to internal ...

In addition to augmented cell survival, the PI3K/AKT signalling pathway directly amplifies contractility. [18] Thus, improved contractility through PI3K/AKT might be a possible explanation for the ...

Herpes simplex virus (HSV), the viral agent causing human genital herpes, recurs easily and poses significant harm to patients, while also being associated with atherosc ...

Conclusion PI3K/AKT signalling is activated in TTC. This activated cell survival cascade might protect cardiomyocytes from cell death and also contribute to rapid regeneration in TTC. Tako-Tsubo ...

The researchers also found that mitochondrial damage in only one pair of ASI neurons could activate the cell's non-autonomous ...